Nepitine is a white, flat face and oblong film-coated tablet with notches on the other face.
As the active substance of nepitis, it contains gabapentin, which is included in the group of antiepileptics.
Contents
- Nephitis Side Effects
- Nepitin Current Price List (2023)
- How is Nepitine Used?
- Nepitine Active Ingredient
- Nepitin User Reviews
What Is Nepitine (600 Mg) Used For?
The film with 50 notches is available in packages containing tablets and is used in the following cases:
- In the treatment of various types of epilepsy (carat), and in addition to the treatment available, unless otherwise specified
- Painful diabetic neuropathy (pain caused by damage to the sensory and motor nerves, which is mostly seen in diabetics), in the treatment of neuropathic pain after postherpetic neuralgia (long-term pain caused by damage to nerves as a result of ozone) and spinal cord injury (damage of nerves involved in the spinal cord).
What Are the Side Effects of Nepitine?
Like all medications, there may be side effects in people who are sensitive to substances contained in Nepitin.
If any of the following happens, stop using Nepitin ‘i and report it to your doctor immediatelyapply to the emergency department of the trail or the nearest hospital: you:
- Serious skin rash
- Fluff and bleeding in the lips, eyes, nose, mouth and genital areas
These are all very serious side effects. All of these very serious side effects are quite rare.
If one of these is present in you, you have a serious allergy to Nepitine. You may need immediate medical attention or hospitalization.
If you notice any of the following, tell your doctor immediately or contact the emergency department of the hospital closest to you.
- Unexplained bleeding Delusions
- Movement disorders(completion of breathing, double vision, abnormal eye movements)
- Tinnitus
- Palpitations, abdominal pain
- Pancreatitis (inflammation of the pancreas)
- Hepatitis, jaundice
- Interruption reactions of the drug (anxiety, insomnia, nausea, pain, sweating), chest pain. In patients with diabetes, fluctuation in blood sugar, elevated liver function tests
These are all serious side effects. Serious side effects are very rare. Urgent medical intervention may be required.
If you notice any of the following, tell your doctor:
Very Common Side Effects
- Viral infections
- Weakness, dizziness, tendency to sleep, ataxia (walking disorder due to difficulty in controlling movement)
- Feeling of fatigue, fever
- Pneumonia, respiratory infection, urinary tract infection, infection, inflammation of the middle ear Leukopenia (decrease in white blood cell count) Hyperglycemia (increased blood sugar levels) Increase in appetite, loss of appetite
- Hostility, confusion and emotional instability(discomfort), depression, anxiety, irritability, etc,
- Feelings such as convulsions, hyperkinesia (excessive movement), dysarthria (speech or language-related disorder), amnesia (unutability), tremors, headaches, paresthesia (numbness), hypoesthesia (decreased sense), coordination disorder, etc, diminished, increased or missing reflexes
- Hypertension (high blood pressure), such as visual disturbances, amblyopia (decreased visual acuity) and diplopia (double vision), vascular dilation Shortness of breath (dispnea), bronchitis, pharyngitis, coughing, rhinitis
- Vomiting, nausea, dental diseases, gingivitis, diarrhea, dyspepsia (indigestion, digestive disorder), constipation (constipation), dry mouth or throat, stomach gas
- Face edema, purpura, rash, itching, acne
- Arthralgia (joint pain), myagia (muscle pain), back pain, twitching
- Impotence (erection or difficulty maintaining an erection), inability to hold urine
- Walking disorder, asthenia, pain, fracture in the body, flu
- Accidental injury, fracture, wear
These are mild side effects of Nepitinidine.
Nepitin Current Price List (2023)
| Date | Label Price | Public Price |
|---|---|---|
| 15.12.2022 | 16681 | 120,1 |
| 09.07.2022 | 122,57 | 88,25 |
| 19.02.2022 | 95,93 | 69,07 |
| 20.02.2021 | 70 | 57,4 |
| 19.02.2020 | 58,36 | 47,86 |
| 19.02.2019 | 52,08 | 46,87 |
| 10.04.2018 | 41,25 | 37,13 |
| 19.02.2018 | 51,96 | 46,76 |
| 20.02.2017 | 45,21 | 40,69 |
| 06.12.2016 | 40,88 | 36,79 |
| 23.02.2016 | 45,46 | 40,91 |
| 22.02.2016 | 45,46 | 36,37 |
| 04.09.2015 | 44,66 | 35,73 |
| 01.06.2015 | 42,98 | 34,38 |
| 11.04.2015 | 42,12 | 33,7 |
| 10.04.2015 | 42,12 |
How is Nepitine Used?
Unless your doctor gives you a separate recommendation, follow these instructions.
Epilepsy also used
Treatment alone: The effective dose of Nepitine is 900-3600 mg/day, taken in three divided doses. In order to prevent new seizures, the time between two doses should not exceed 12 hours.
Adults: The initial dose is usually between 300 mg and 900 mg. Nepitin 600 mg Notched film tablet, thanks to the notch can be divided into two doses equal 300 mg dose adjustment. Depending on the condition of your disease, your doctor may increase the dose (maximum 3600 mg). Take the dose indicated by your doctor at three times, morning, noon and evening. The time between two doses should not exceed 12 hours.
If you are taking a high dose and the dose adjustment is fast, the risk of dizziness increases during the dose adjustment period. It is not necessary to monitor the plasma levels of gabapentin to optimize treatment.
Use in neuropathic pain:
Initial dose it is usually between 300 mg and 900 mg. Nepitin 600 mg Notched film tablet, thanks to the notch can be divided into two doses equal 300 mg dose adjustment. Depending on the condition of your disease, your doctor may increase the dose (maximum 3600 mg). Take the dose indicated by your doctor at three times, morning, noon and evening. The time between two doses should not exceed 12 hours.
Use in postherpetic neuralgia:
- In the treatment of postherpetic neuralgia, the maintenance dose of gabapentin should be adjusted according to the clinical effect and be regulated according to the instructions given below:
- The effect is usually seen in the dose range of 1800-2400 mg/day, but in some cases it may be necessary to increase the dose to a maximum of 3600 mg/day.
Adults: The initial dose is usually between 300 mg and 900 mg. Nepitin 600 mg Notched film tablet, thanks to the notch can be divided into two doses evenly, making a 300 mg dose adjustment. Depending on the condition of your disease, your doctor may increase the dose (maximum 3600 mg). Take the dose indicated by your doctor at three times, morning, noon and evening. The time between two doses should not exceed 12 hours.
Use in diabetic neuropathy:
- The effective dose of gabapentin in the treatment of diabetic neuropathy is 9003600 mg/day, taken in the form of three divided doses.
- The efficacy and safety of gabapentin for more than 5 months in the treatment of neuropathic pain, such as postherpetic neuralgia, has not been studied.
- Nepitine is for oral use, should be swallowed with some water without chewing with or without meals.
The Use of Nephitis in Children
- Children under 3 years of age do not have enough experience with additional treatment.
- the initial dose of gabapentin for additional treatment in children aged 3-12 years is 10-15 mg/kg per day, divided into three equal doses per day. Effective dose can be reached by increasing the dose within three days. If your child is 5 years and older, the effective dose of gabapentin is 25-35 mg/kg divided into three equal doses per day.
- If your child is 3 and 4 years old, the effective dose is 40 mg/kg, divided into three equal doses per day. Doses of up to 50 mg/kg per day have been well tolerated in clinical trials. The time interval between doses you give your child should not exceed 12 hours.
- Children under 12 years of age do not have enough experience with monotherapy.
The efficacy and safety of gabapentin in the treatment of postherpatic neuralgia has not been studied for children.
The Use of Nepithin in the Elderly
If kidney function is not impaired, you do not need to adjust the dose; in case of kidney disorder, the dose adjustment should be adjusted as described below.
Renal failure, liver failure:
- If your kidney function is impaired, you should use a reduced dose. The dose of Nepitine you should use will be adjusted by your doctor according to the severity of your disease.
- Dose reduction, discontinuation or replacement with an alternative anticonvulsant drug should be done gradually and spread over at least a week.
- The use of gabapentin in children younger than 12 years of age with impaired renal function has not been studied.
If you have an impression that the ‘in effect of Nepitine is very strong or weak, talk to your doctor or pharmacist.
If you forget to take nepithin:
If you forget to take Nepitin and you are not close to the time when you should take the next dose, take it as soon as you remember the forgotten dose. Take the remaining doses on your own time.
Do not take double doses to offset forgotten doses.
Do not stop using nepithin unless your doctor tells you to. If your treatment is to be terminated, your treatment should be terminated gradually for at least 1 week. If you suddenly or without telling your doctor, you may be at increased risk of seizures.
In What Situations should Nepitine not be used?
- If you have hypersensitivity to gabapentine or any substance in the composition of Nepitin, you should,
- If you have acute pancreatitis, do not use this medicine.
In What Situations should Nepitine be Used Carefully?
Since it can increase the severity of seizures, if mixed seizures involving absences occur, you should use it with caution and immediately contact the physician.
- If you have kidney disease,
- If you have had serious mental illness
- Has a history of psychotic illness
- If you are taking medications to treat depression, use this medication with caution.
- Suicidal thoughts and behavior have been reported in patients treated with this drug. Therefore, patients should be closely monitored for suicidal thoughts and behavior. When suicidal thoughts and behaviors occur, the patient and the patient should be advised to seek medical support.
If these warnings apply to you, even at any time in the past, please consult your doctor.
Is Nepitine Used with Food and Drink?
The interaction of nepitis with alcohol can have serious consequences. Consult your doctor before taking the medication.
Food has no effect on gabapentin absorption.
It should not be used concurrently with alcoholic beverages when being treated with nepitis.
Is Nepitin Used in Pregnancy?
Consult your doctor or pharmacist before using the medicine.
If you notice that you are pregnant during your treatment, consult your doctor or pharmacist immediately.
- Gabapentin passes into breast milk. The effect on children fed breast milk is unknown and the possibility of its effect cannot be ruled out. For this reason, the use of gabapentin during breastfeeding should be avoided; it should be decided to end the intake of breastfeeding or the drug, taking into account the importance of the drug for the mother.
Vehicle and machinery use
Nepitine has a small or moderate impact on vehicle and machine use. Because it acts on the central nervous system, it can cause drowsiness, dizziness, or similar symptoms and can be dangerous for people driving vehicles and machinery. Do not use vehicles and machinery until it is determined that the ability of the patients to drive vehicles and machinery is not affected during the use of Nepitine.
Nepitine Active Ingredient
Active substance: Each film tablet 600 mg gabapentin includes.
Auxiliary substances: Kopovidone, poloxamer 188, corn starch, magnesium stearate, hydroxypropyl methyl cellulose (5 cps), talc.
The Use of Nepitine in conjunction with Other Drugs
- If you are taking antacid containing any aluminum and magnesium, you can take Nepitin about 2 hours after taking an antacid of Nepitini, as it can reduce the absorption of Nepitin in the stomach.
- No interaction was observed between nepitis and phenobarbital, phenytoin, valproic acid or carbamazepine.
- Nepitin has no effect on other antiepileptic drugs and oral contraceptives containing norethindrone and/or ethinylestradiol. If you use it with antiepileptic drugs that are known to reduce contraceptive effectiveness, you should consider the failure of contraception.
- Since false positive readings are reported with some laboratory tests, when it is necessary to have a urine test, report Nepitin to your doctor or the hospital where you are going.
- Its combined use with cimetidine produces a slight decrease in the renal excretion of Gabapentin, which is not clinically significant. No change in renal excretion was observed in its use with Probenecid.
- Its intake along with valerian, yellow cantarone, kava pepper and gotu kola should not be used in combination with gabapentin, as it can increase central nervous system depressions.
- Its use with primrose should not be taken together as it may reduce the seizure threshold.
- • Alcove, It can exacerbate some side effects (somnolans) related to the central nervous system. Therefore, it should not be taken simultaneously.
If you are currently taking any prescription or over-the-counter medications or have recently used them, please tell your doctor or pharmacist about them.
Nepitin User Reviews
The medicine I use because of diabetes is excessive sleepiness.
User Comment
A few days of being nervous together gives an effect of restlessness.
User Comment